Profhilo and Profhilo Structura are both injectable treatments that utilize hyaluronic acid to enhance skin quality, but they differ significantly in formulation, application, and intended outcomes.
Core Differences
| Feature | Profhilo | Profhilo Structura |
|---|---|---|
| Purpose | Skin hydration, elasticity, and overall quality | Structural support, lifting, and contouring |
| HA Concentration | 64 mg/2 ml | 90 mg/2 ml |
| Injection Depth | Superficial dermis | Deep subcutaneous fat (dWAT) |
| Injection Technique | 5 BAP points per side | Targeted cannula or needle |
| Treatment Areas | Face, neck, décolletage, hands | Cheeks, jawline, temples |
| Results Timeline | Subtle improvements over weeks | Noticeable lift within 4–6 weeks |
| Maintenance | Every 6 months | Every 9–12 months |
Mechanism of Action
- Profhilo is a bio-remodelling injectable composed of ultrapure hyaluronic acid that spreads evenly beneath the skin after injection. It hydrates from within, stimulates collagen and elastin production, and enhances your skin’s glow, firmness, and elasticity.
- Profhilo Structura utilizes a more advanced formulation of cross-linked hyaluronic acid to offer structural and volumizing benefits, particularly in areas with greater laxity. It targets specific areas like the lower face, jawline, and cheeks, where sagging and loss of contour are more pronounced.
Treatment Considerations
- Profhilo is ideal for individuals seeking overall skin rejuvenation and hydration, particularly those in the early stages of skin aging.
- Profhilo Structura is better suited for individuals experiencing moderate to significant skin laxity and structural loss, often seen in mature skin. It offers more pronounced lifting and structural enhancement.
Summary
| Treatment | Best For | Key Benefit |
|---|---|---|
| Profhilo | Early signs of aging, overall skin health | Hydration and skin quality |
| Profhilo Structura | Moderate to severe skin laxity | Structural support and lifting |
If you’re considering these treatments, book in with us to determine which option aligns best with your aesthetic goals and skin condition.

